Understanding Fibromyalgia: The Key to Unlocking Relief

Learn about fibromyalgia causes, diagnosis, treatment, and management strategies.

Everything You Need to Know About Fibromyalgia

Including Causes and The Latest Evidence Based Treatments


Fibromyalgia is a chronic condition affecting millions of people around the globe. It is characterised by widespread muscle and joint pain, fatigue, and a multitude of other symptoms such as difficulty sleeping, cognitive difficulties, and depression. There is no known cause or cure for fibromyalgia, but there are treatments available to help manage the symptoms. This article will cover everything you need to know about fibromyalgia, including its assumed causes, risk factors, diagnosis, and treatment. In addition, we will discuss coping strategies and where to locate support. By the conclusion of this article, you should have a grasp of fibromyalgia and its various treatment options.



What causes fibromyalgia?

Fibromyalgia is believed to be caused by a combination of genetic, environmental, and psychological factors. It can be caused by physical or emotional trauma, an infection, or a preexisting condition such as lupus or rheumatoid arthritis. People with fibromyalgia frequently experience widespread muscle and joint pain, as well as fatigue, difficulty sleeping, memory issues, anxiety, melancholy, and difficulty concentrating. Alterations in serotonin and other brain compounds also contribute to the development of this disorder. Typical treatments involve medication to manage pain and other symptoms, lifestyle changes such as regular exercise, and stress management techniques such as relaxation therapy or cognitive-behavioral therapy.


Is fibromyalgia autoimmune or neurological? The complex disorder fibromyalgia affects the musculoskeletal system and is characterised by pervasive pain and fatigue. The cause of fibromyalgia is still unknown, and whether this condition is autoimmune or neurological in character is still in debate. Typically, it is believed that a problem with the nervous system, which can make a person more sensitive to pain signals, is to blame. Connections have been made between fibromyalgia and other autoimmune conditions, such as rheumatoid arthritis, but research has yet to conclusively demonstrate that this condition has an autoimmune basis. It is more likely a combination of genetics, environmental triggers, emotional stressors, and hormonal imbalances.


Other Potential Causes of Fibromyalgia

Fibromyalgia's etiology is unknown. It's believed that genetic predisposition plays a significant role, however, our diet, lifestyle, and environment also have a great effect.

An untreated gastrointestinal disorder, such as a parasite or pathogenic bacterial overgrowth, is frequently the root cause. In other instances, a traumatic event or chronic stress causes severe dysfunction of the HPA axis and triggers a stress response, contributing to the development of fibromyalgia.

Patients frequently attribute the onset of symptoms to a precipitating event, such as a flu-like illness or trauma, be that physical or emotional. Common triggers for this condition include Lyme disease, Epstein-Barr virus, mold exposure, etc.

Possible mechanisms include:

  •  Mitochondrial dysfunction i.e.. changes in glycolysis, increased lactate production, and low ATP and phosphocreatine synthesis
  •  Altered cerebral blood flow, neurotransmitter status (especially serotonin, which is found to be low in fibromyalgia patients) and increased pain perception
  • Nutritional deficiency e.g. magnesium, B-complex, vitamin D, B12 etc
  •  Adrenal hypo responsiveness and circadian rhythm abnormalities
  •  Immune dysregulation


Fibromyalgia risk factors

The precise cause of fibromyalgia has not yet been determined but the available research suggests that the following factors increase the risk of development:

  • Sex. Currently, the majority of fibromyalgia patients are female.
  • Age. You are most likely to be diagnosed during middle age. It occurs in children but your risk increases as you age.
  • Family ancestry. Having close relatives with fibromyalgia, increases your risk of developing the condition.
  • History of other illnesses. Despite fibromyalgia not being a form of arthritis, rheumatoid arthritis (RA) may increase the likelihood of developing fibromyalgia. Approximately 30% of lupus patients are also affected by fibromyalgia.
  • Ongoing research is continuing to contribute to a greater understanding of the etiology and nature of this condition.


Are chronic fatigue and fibromyalgia related?

A person with chronic fatigue and fibromyalgia experiencing pain

Chronic fatigue and fibromyalgia are co-occurring medical conditions. While the precise causes of both are unknown, researchers believe they may be related. Chronic fatigue is characterised by extreme exhaustion and a lack of energy for which there is no clear underlying medical cause. Fibromyalgia is a condition characterised by widespread pain throughout the body as well as tenderness at specific pressure sites. The overlap between the two conditions suggests a connection between them; however, additional research is required to determine how they may be related.


What age does fibromyalgia usually start?

Typically, fibromyalgia begins in maturity, between the ages of 20 and 50. It is more prevalent in women than in men, and it is believed that 3-6% of the world's population has it. Chronic generalised pain, tenderness, fatigue, depression, and anxiety are common symptoms as well as difficulty sleeping, morning stiffness, concentration and memory issues, migraines, and irritable bowel syndrome (IBS). These symptoms amongst others have led researchers to believe it appears to involve alterations in the way the brain and spinal cord process pain signals. Typically, it is treated with lifestyle modifications such as exercise, stress management, and a healthy diet. In addition, medication may be prescribed to alleviate pain or enhance sleep quality. It is essential to work with a doctor to develop an individualised treatment plan that is optimal for your unique needs.

A person lying on bed with fibromyalgia


What are usually the first signs of fibromyalgia?

The initial manifestations of fibromyalgia can vary from person to person, but the most common symptoms include muscle pain, joint stiffness, and migraines. The most prominent symptom of fibromyalgia is generalised pain. In contrast to arthritis, the tenderness is in the muscles and tendons, not the bones or joints. Typical locations of discomfort include the neck, shoulders, back, and hips. Furthermore, there may be a diffuse hypersensitivity where the sensory components of the neuromuscular system are overly sensitive, resulting in heightened sensitivity to various stimuli. This heightened sensitivity is most intense in the morning and has been compared to flu symptoms, burning, pulsating or stabbing pain.


What are the main symptoms of fibromyalgia, besides pain and tenderness?

Fatigue is a common symptom of fibromyalgia. Some physicians believe that fibromyalgia and chronic fatigue syndrome are caused by the same underlying condition as they occur in sync so frequently. The severity of fatigue can differ from mild to incapacitating. At its worst, the exhaustion can be so severe that individuals have difficulty maintaining employment. No amount of twilight sleep or respite during the day is effective in reducing fatigue.

Another common symptom is the effect on the brain and mental clarity known as "fibrofog." This refers to the inability to concentrate, memory loss, and depression that occur with fibromyalgia.

Further symptoms are insomnia, migraines, nervousness, numbness, dizziness, depression, and digestive issues such as IBS.

If you experience any of these symptoms for more than three months, it is crucial that you see a doctor for additional testing, as early diagnosis is essential for managing this complex condition.


What is the pain like with fibromyalgia?

The pain associated with fibromyalgia is deep, intense, and pervasive. The quality is frequently described as a dull, wide-spread pain, but can also be sharp, burning, or stabbing. It may come and go without warning, or persist for extended periods. Fibromyalgia pain is frequently worse in the morning and night. Additionally, exposure to frigid weather, stress, or physical activity can exacerbate the condition. Pain associated with fibromyalgia can be so severe that it hinders daily activities such as walking, reclining, or standing for extended periods. People with fibromyalgia frequently report that their constant discomfort makes them exhausted while simultaneously making it difficult to sleep. It is not merely a physical condition; it is a complex disorder that affects individuals in a variety of mental and physical ways.


Why does fibromyalgia cause fatigue?

Illustration showing fibromyalgia symptoms

It is likely caused by an overabundance of compounds in the brain that regulate pain signals and mood. This can result in an increase in stress hormones, which exacerbates fatigue. Inadequate sleep or sleep deprivation also contributes to fibromyalgia-related fatigue, as these conditions make it more difficult for the body to recuperate from physical activity or mental stress. Additionally, certain fibromyalgia medications may induce fatigue as a side effect. All of these factors can make it difficult for individuals with fibromyalgia to maintain their energy levels throughout the day, causing them to feel more exhausted.



How can I test myself for fibromyalgia?

“Do I have fibromyalgia?” Answer the following
 
Quiz 1 

Quiz 2  



What is the impact of fibromyalgia on the brain?

Fibromyalgia has been linked to alterations in brain regions that process pain signals, emotions, and cognitive performance. Fibromyalgia patients may experience an increase in pain sensitivity, fatigue, melancholy, anxiety, memory problems, and concentration difficulties. Changes in the levels of neurotransmitters such as serotonin or norepinephrine can result in these difficulties. In addition, research indicates that people with fibromyalgia have high levels of brain inflammation. This inflammation can make it more difficult for neurons and other cells to communicate, which can exacerbate symptoms. In order to improve their overall quality of life, fibromyalgia patients require treatment plans that address both their physical and mental health requirements.


Is there a test for fibromyalgia?

Fibromyalgia is diagnosed using diagnostic criteria and laboratory tests that either exclude other diseases that could be causing symptoms or diagnose diseases that coexist with fibromyalgia. Diagnostic criteria include:

1. History of persistent widespread pain extending over three months

2. Pressure-induced pain in at least 11 of 18 designated tender sites

3. Exclusion of other potential causes of the symptoms

Lab tests used to help diagnose fibromyalgia may include the following:

1. Complete blood count (CBC)

2. C-reactive protein (CRP)

3. Thyroid stimulating hormone (TSH)

4. Rheumatoid factor (RF)

5. Antinuclear antibody test (ANA)

6. Creatine kinase (CK)

7. Erythrocyte sedimentation rate (ESR)


Misdiagnosis Fibromyalgia Risks

Fibromyalgia can be difficult to diagnose because several other conditions can produce similar symptoms and can even coexist with it. Fibromyalgia shares symptoms with rheumatoid diseases such as osteoarthritis, rheumatoid arthritis, lupus, and ankylosing spondylitis. Consequently, when diagnosing fibromyalgia, lab tests may be ordered to rule out other potential causes, including:

A complete blood cell count (CBC) can check for anemia, which can cause weakness and fatigue

a misdiagnosis of fibromyalgia due to abnormal CBC results


An erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP) test is recommended, can detect diseases that cause inflammation, such as polymyalgia rheumatica. A blood calcium level test, a low level can cause muscle cramps


Differential diagnosis


What is the treatment for fibromyalgia?


A person engaging in low-impact exercises to manage fibromyalgia symptoms

As the preceding list demonstrates, many of these causes are interrelated, and there is often no singular underlying cause of fibromyalgia or any other chronic illness. It is a combination of multiple or possibly all of the aforementioned. Because determining the root cause can be difficult, it is often recommended that you locate a functional medicine doctor in your area who can help you determine the root cause. You are not required to mask your symptoms with analgesics and antidepressants, there are physicians who can help you.



What alleviates fibromyalgia flare-ups?

Flare-ups of fibromyalgia can be difficult to manage and cause significant discomfort. Getting regular exercise, practicing good sleep, reducing stress, maintaining a healthy diet, and taking medications as needed can all help to reduce the severity of flare-ups. Exercise helps maintain the mobility and flexibility of your muscles, while proper sleep practices ensure you get enough restful sleep. Reducing stress is essential for overall health and may reduce the severity of flare-ups. Eating a healthy, well-balanced diet is essential for your overall health and managing fibromyalgia symptoms. Lastly, taking the prescribed medications will assist you in managing your pain and other fibromyalgia symptoms. You can reduce the severity of your flares and improve your quality of life by following these measures.


10 Root Causes Of Fibromyalgia

Gluten Intolerance

A person experiencing gastrointestinal symptoms

Gluten has been linked to more than 55 diseases and is often called the "big masquerader." The reason being that the majority of the symptoms of gluten intolerance are not digestive in nature but rather neurological, such as pain, cognitive impairment, sleep disturbances, behavioural issues, fatigue, and depression.


Candida Overgrowth

Candida is a yeast, and a very small amount of it lives in your intestines. But when it grows too much, candida breaks down the wall of the intestines and gets into the bloodstream. This lets toxic waste into your body and causes a number of uncomfortable symptoms, such as brain fog, fatigue, digestive problems, and pain.

Want to learn more about what causes Candida overgrowth and how to eliminate it? Check out our Candida Control Resource Bundle!


Thyroid

A butterfly-shaped thyroid gland located in the neck, producing hormones that regulate metabolism


More than half of the people with thyroid issues are totally unaware that the thyroid is causing the issue, and 90% of these have hypothyroidism, or an underactive thyroid gland. Six different blood markers need to be checked in order to figure out how well the thyroid gland is working, and optimal levels instead of the standard reference range must be tested to uncover the issue. Getting thyroid levels into an optimal range typically alleviates fatigue, brain fog, sleep disturbances, and depression.


Vitamin Deficiencies

A chart showing various vitamin deficiencies

Magnesium, vitamin D, and B12 deficiency are the most common vitamin deficiencies seen in fibromyalgia patients. Patients have been known to completely reverse their fibromyalgia symptoms with magnesium alone. The best way to measure magnesium is checking a red blood cell (RBC) magnesium level, which can be ordered by your doctor and tested through any conventional lab.


Small Intestine Bacterial Overgrowth (SIBO) and Leaky Gut

Bacteria outnumber our own cells both inside and outside of us. When these bacteria get out of balance through the use of antibiotics or a sugar-rich diet, we can lose our ability to digest and absorb nutrients, particularly B12. Gluten can cause patients to develop SIBO and leaky gut, and SIBO and leaky gut can lead to gluten and other food intolerances. It’s a catch-22 and a vicious cycle. You must first "fix the gut" in patients suffering with fibromyalgia or other chronic illness.


Adrenal Fatigue

Adrenal fatigue is a result of chronic stress. Chronic pain is a stressor on the adrenal glands, though typically not the initial stressor. The initial stressor is often something such as food intolerances, Candida, mercury toxicity, vitamin deficiencies, or mycotoxins. The goal when approaching this condition is to support the adrenals with adaptogenic herbs while searching for the root cause of the stress in order to correct it.


Mycotoxins

Mycotoxins are toxic substances produced by toxic moulds. Approximately 25% of people carry the genes that make us vulnerable to mycotoxins. Typical mould testing in the environment only checks for the amount of mould spores but does not look for mycotoxins. To test for these toxins, we use a urine mycotoxin test.


Mercury Toxicity

A diagram showing sources of mercury toxicity

To discover mercury toxicity patients have to source a biological dentist to take out their mercury amalgam fillings. Mercury is toxic to our bodies and can be one piece of the puzzle for those with fibromyalgia and other chronic illnesses such as chronic fatigue syndrome, autoimmune diseases, neurological disorders, and cancer. The recommendation is to then implement heavy metal testing using a pre-and post-DMPS urine challenge test.


MTHFR Mutations

This is discovered by a genetic test which you can receive at any conventional lab. The larger number of mutations you have of the MTHFR gene, the less able you are to methylate and detoxify particularly toxins such as mercury and lead. 1 And the more mutations you have of this gene, the higher your requirements for methyl-B6, methyl-B12, and folinic acid are in order to keep your detoxification pathways working properly.


Glutathione Deficiency

Glutathione, a molecule, is the most critical part of our body’s detoxification system. Glutathione gets recycled in our body unless our toxic burden gets too high or we lack GSTM1 and GSTP1, the enzymes needed to recycle and produce glutathione. Taking a glutathione supplement or the precursors (NAC, alpha-lipoic acid, milk thistle) often helps patients dramatically with fatigue.


How we treat fibro at The Health Collective

This is a common treatment plan for Fibromyalgia

  •  Reduce muscle pain, inflammation and spasm

  •  Reduce oxidative stress

  •  Support neurotransmitter production

  •  Support mitochondrial function

  •  Support circulation (of blood to brain and muscles)

  •  Support adrenal function

  •  Support thyroid function

  •  Support immune response

  •  Address digestive dysfunction

  •  Identify/address any nutritional deficiencies

  •  Improve sleep quality

  •  Manage stress


What is the best treatment protocol for fibromyalgia?

a person's best treatment protocol for fibromyalgia

A combination of osteopathy, naturopathy, convential medicine and acupuncture/traditional Chinese medicine. is the most effective form of treatment.

Osteopathy is a form of manual therapy that focuses on alleviating discomfort in the muscles and joints and restoring mobility.

Naturopathy is an alternative form of medicine that employs natural remedies such as herbs, vitamins, minerals, lifestyle modifications, and dietary modifications to treat symptoms.

Herbal remedies, acupuncture, moxibustion, and massage are all components of Chinese medicine, a method of healthcare that has been practiced for thousands of years.

All three methods can be combined to lessen the impact of fibromyalgia on an individual's life. They can also provide relief from fibromyalgia-related chronic pain, fatigue, and other symptoms. This combination of treatments has been demonstrated to be one of the most effective methods to treat this condition.

To treat fibromyalgia, it is essential to adopt a personalised approach. Every fibromyalgia patient should endure a careful evaluation prior to beginning any treatment for the best outcome.


In summation, living with fibromyalgia can be challenging and frustrating, but you do not have to face it alone. Our clinic has a team of skilled medical experts who are knowledgeable about fibromyalgia and can offer you the support and direction you need to control your symptoms and improve your quality of life.

We are here to help you, whether this fibromyalgia is a new diagnosis or one you have had for some time. Our staff can work with you to develop a thorough treatment plan that is customised to your needs. We provide a range of therapeutic options, from physical therapy to dietary changes, all of which are intended to help you control your symptoms and improve your general health.

If you find the right support and care, living with fibromyalgia is not impossible. For more information about our services and how we can help you on your road to better health, please get in touch with our clinic. By working together, we can better understand and treat this condition, leading to better outcomes for everyone affected.

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